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2023 Experiential Internship - Tau Biology


Location: Owensboro, Kentucky
Type: Non-Remote
Posted on: January 13, 2023
Abbvie Posted Under: Owensboro, Kentucky jobs in Other; Other jobs in zipcode 42304 Posted On: 2023-01-11 ABOUT ABBVIE AbbVie's mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women's health, and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at Follow -@abbvie -on -Twitter, -Facebook, -Instagram, -YouTube, -and -LinkedIn. TAU BIOLOGY INTERNSHIP OVERVIEW Envision spending your summer working with energetic colleagues and inspirational leaders, all while gaining world-class experience in one of the most dynamic organizations in the pharmaceutical industry. This is a reality for AbbVie's Experiential Interns. Tau misfolding plays a key role in Alzheimer's disease (AD), as well as other neurodegenerative diseases. There has been an explosion in novel science related to the release, spread, and uptake of tau aggregates in pathology conditions by numerous in vitro and in vivo approaches. We are interested in understanding the characteristics of tau aggregates which are responsible for the seeding and propagation of pathology using in vitro culture systems. The intern will help to perform and analyze in vitro cell culture-based assay experiments as well as learn transcriptomic methods and analyses. KEY RESPONSIBILITIES INCLUDE: Help design, perform, and analyze in vitro and in vivo experiments in Alzheimer's disease models using biochemical and/or molecular techniques Learn aseptic technique to work with hiPSC neurons and rodent primary neuronal cultures Learn how to use a high-content confocal microscope to collect high resolution image data and perform quantitative data analysis as well as learn IHC and similar techniques Learn transcriptomics and analysis on samples ranging from primary mouse neuron cultures to postmortem Alzheimer's Disease tissues. MINIMUM QUALIFICATIONS Currently enrolled in university, pursing a Bachelor's degree in Biochemistry, Molecular Biology, Neuroscience, or other related field Must be enrolled in university during the internship period Must be highly motivated, detail-oriented with strong verbal and written communication skills PREFERRED QUALIFICATIONS: Molecular or system neuroscience background / interest Previous work with stem cells, primary cultures and / cell lines Microscopy skills including immunofluorescence and live cell imaging Biochemical assays such as protein extraction, ELISA, Western blot Comfortable using computer programs such as Microsoft, PowerPoint, Excel and Google Docs BENEFITS AND AMENITIES Competitive pay Travel, transportation and lodging support for eligible students EQUAL EMPLOYMENT OPPORTUNITY At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic. Apply for this job, view similar jobs, and more at ! Skills: Salary: -