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2023 Experiential Internship - DMPK Research (Illinois)

Abbvie

Location: Owensboro, Kentucky
Type: Non-Remote
Posted on: January 13, 2023
**ABOUT ABBVIE** AbbVie’s mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women’s health, and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on Twitter, Facebook, Instagram, YouTube, and LinkedIn.  **DMPK RESEARCH INTERNSHIP OVERVIEW** Envision spending your summer working with energetic colleagues and inspirational leaders, all while gaining world-class experience in one of the most dynamic organizations in the pharmaceutical industry. This is a reality for AbbVie’s Experiential Interns. The DMPK Research Intern will investigate and optimize hepatocyte spheroids, co-cultures and other complex in vitro models for several applications within the drug metabolism and pharmacokinetics disciplines (i.e., clearance prediction, estimation of the fraction of drug metabolized by individual enzymes, metabolite identification). Studies will include but are not limited to the optimization of seeding/culturing methods for mono-/co-cultures of liver spheroids, development of protocols for fabricating spheroids with hepatocytes from preclinical species, evaluating commercially available complex in vitro models, demonstration of clearance prediction for compounds that are slowly metabolized, and establishment of protocols for determining individual enzyme involvement in metabolism. **KEY RESPONSIBILITIES INCLUDE:** - Prepare cell cultures using sterile techniques - Record experimental conditions and data accurately - Perform quantitative analysis **MINIMUM QUALIFICATIONS** - Currently enrolled in university, pursuing a Bachelor’s, Master’s, PhD or Phar mD in Biology, Chemistry, Biochemistry, Cell Biology, Pharmaceutical Sciences, Pharmacology, Toxicology, or other related field - Must be enrolled in university during the internship period - Must have enthusiasm for science and eagerness to learn **PREFERRED QUALIFICATIONS** - Exposure to liquid chromatography, mass spectrometry, and other techniques for quantitative analysis of small molecule drugs - Knowledge of cell biology and sterile technique **BENEFITS AND AMENITIES** - Competitive pay - Travel, transportation and lodging support for eligible students - Exposure and learning opportunity from world class scientists **EQUAL EMPLOYMENT OPPORTUNITY** At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic. Skills: Salary: -